Korean J Nephrol.  2007 Jul;26(4):465-468.

A Case of Cystadenocarcinoma of the Pancreas in a Patient with Autosomal Dominant Polycystic Kidney Disease

• Lee SY
• Yang YJ
• Jang DS
• Lee YM
• Na KR
• Lee BS
• Lee KW
• Shin YT

Abstract

Polycystic kidney disease is an autosomal dominant disease that may be associated with liver and pancretic cysts. Mitral valve prolapse and intracranial berry aneurysms are also well-known manifestations of autosomal dominant polycystic kidney disease (ADPKD). Cystadenocarcinoma of the pancreas is uncommon and accounts for only 1% of primary pancreatic malignancies. Few cases were reported to have an association of ADPKD and pancreatic malignancies. We report a 63-year-old man with ADPKD who was admitted to our hospital with anorexia and severe weight loss. After abdominal CT and histologic examination, he was diagnosed as pancreatic cystadenocarcinoma with lung, spleen, and liver metastasis. To prolong the life of the patient, we tried gemcitabine and cisplatin combination chemotherapy. But the patient died 2 months after diagnosis due to the disease progression.

Keyword

Polycystic kidney diseases; Pancreatic neoplasms; Cystadenocarcinoma

MeSH Terms

Anorexia
Cisplatin
Cystadenocarcinoma*
Diagnosis
Disease Progression
Drug Therapy, Combination
Humans
Intracranial Aneurysm
Liver
Lung
Middle Aged
Mitral Valve Prolapse
Neoplasm Metastasis
Pancreas*
Pancreatic Neoplasms
Polycystic Kidney Diseases
Polycystic Kidney, Autosomal Dominant*
Spleen
Tomography, X-Ray Computed
Weight Loss
Cisplatin