Korean J Nephrol.  2003 Nov;22(6):773-776.

Coexistence of IgA Nephropathy and Post-infectious Glomerulonephritis

Affiliations
  • 1Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. ysshincmc@catholic.ac.kr
  • 2Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Abstract

A 33-year-old man was admitted with macroscopic hematuria and systemic edema appearing after an acute upper respiratory tract infection. On admission, hypertension, nephrotic syndrome were evident together with a decreased renal function. Renal biopsy showed markedly increased mesangial cells acompanied with increase of endocapillary cells including neutrophils. Immunofluorescence microscopy showed granular deposits of C3 and IgA. Electron Microscopy revealed so-called "hump" on the subepithelial area. These features were consistent with the coexistence of IgA nephropathy (IgAN) and post-infectious glomerulonephritis. It is not clear about the prognosis and the therapeutic regimen in the patient who develop above situation. Although the patient showed still persistent proteinuria, high dose steroid therapy was probably useful for improving the disease.

Keyword

Ig A nephropathy; Postinfectious glomerulonephritis; Coexistence

MeSH Terms

Adult
Biopsy
Edema
Glomerulonephritis*
Glomerulonephritis, IGA*
Hematuria
Humans
Hypertension
Immunoglobulin A*
Mesangial Cells
Microscopy, Electron
Microscopy, Fluorescence
Nephrotic Syndrome
Neutrophils
Prognosis
Proteinuria
Respiratory Tract Infections
Immunoglobulin A
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