J Korean Assoc Oral Maxillofac Surg.  2015 Oct;41(5):265-269. 10.5125/jkaoms.2015.41.5.265.

Aplastic anemia and dental implant rehabilitation: a clinical trial

Affiliations
  • 1Department of Oral and Maxillofacial Surgery, School of Dentistry, Chonnam National University, Gwangju, Korea. ashgray79@gmail.com

Abstract

The purpose of this study was to investigate implant-supported restoration as a technique for restoring missing teeth in patients with aplastic anemia. Recurrent bleeding from wound sites leads to persistent release of iron in the tissue. Excessive iron in tissue is related to clinical findings, including fibrosis, poor wound healing, and high level of angiogenesis, which are possible etiological factors of reduced osseointegration. A 44-year-old female patient with aplastic anemia was treated with multiple endosseous implants throughout the mandible and in the posterior region of the maxilla. After 14 implants were placed, radiological and clinical parameters were assessed during the follow-up period. Marginal bone did not change significantly during the follow-up period. The fine trabecular bone in intimate contact and enclosing the implant fixture was sufficient for successful osseointegration. None of the 14 implants were associated with compilations during the seven-year experimental period. This study suggests that dental implant procedures are a safe and reliable treatment option for restoration of missing dentition in patients with aplastic anemia.

Keyword

Aplastic anemia; Dental implants; Rehabilitation

MeSH Terms

Adult
Anemia, Aplastic*
Dental Implants*
Dentition
Female
Fibrosis
Follow-Up Studies
Hemorrhage
Humans
Iron
Mandible
Maxilla
Osseointegration
Rehabilitation*
Tooth
Wound Healing
Wounds and Injuries
Dental Implants
Iron
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