Gut Liver.  2014 Nov;8(6):590-597. 10.5009/gnl14081.

An Overview of Eosinophilic Esophagitis

• Park H

• KMID: 2070074
• DOI: http://doi.org/10.5009/gnl14081

Abstract

Eosinophilic esophagitis (EoE) is a chronic, immune/antigen-mediated esophageal disease affecting both children and adults. The condition is characterized by an eosinophilic infiltration of the esophageal epithelium. Symptoms of esophageal dysfunction include dysphagia, food impaction and symptoms mimicking gastroesophageal reflux disease. Endoscopic examination typically reveals mucosal fragility, ring or corrugated mucosa, longitudinal furrows, whitish plaques or a small caliber esophagus. Histologic findings of >15 eosinophils per high-power field is the diagnostic hallmark of EoE. An elimination diet, topical corticosteroids or endoscopic dilation for fibrostenotic disease serve as effective therapeutic option.

Keyword

Eosinophilic esophagitis; Gastroesophageal reflux; High-power field

MeSH Terms

Administration, Topical
Adrenal Cortex Hormones/*therapeutic use
Adult
Child
Deglutition Disorders/etiology
Diagnosis, Differential
Eosinophilic Esophagitis/complications/diagnosis/*therapy
Esophageal Stenosis/etiology/*surgery
Esophagoscopy
Esophagus/*pathology
*Food Habits
Gastroesophageal Reflux/diagnosis
Humans
Adrenal Cortex Hormones