J Korean Diabetes Assoc.  2003 Apr;27(2):165-171.

A Case of Primary Antiphospholipid Syndrome in a Patient with Diabetes Presenting as Foot Ulcer

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Antiphospholipid syndrome is a disorder characterized by recurrent vascular thrombosis, pregnancy loss and thrombocytopenia, and the presence of the lupus anticoagulant or a positive anticardiolipin test. A link of antiphospholipid syndrome to diabetes mellitus has not been established. There have been no reports of large artery thrombosis associated with antiphospholipid syndrome or diabetes mellitus. We present a case of an adult with large artery thrombosis, elevated anticardiolipin antibodies and lupus anticoagulant associated with diabetes. The patient was managed by successful primary percutaneous transluminal angioplasty and stent implantation, with accompanying anticoagulation therapy. To our knowledge, this is the first case where the occluded large artery was treated with primary stent implantation in primary antiphospholipid syndrome with diabetes mellitus

Keyword

Diabetes mellitus; Antiphospholipid syndrome; Large artery thrombosis; Stent implantation

MeSH Terms

Adult
Angioplasty
Antibodies, Anticardiolipin
Antiphospholipid Syndrome*
Arteries
Diabetes Mellitus
Foot Ulcer*
Foot*
Humans
Lupus Coagulation Inhibitor
Pregnancy
Stents
Thrombocytopenia
Thrombosis
Antibodies, Anticardiolipin
Lupus Coagulation Inhibitor
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