An Experimental Study on the Changes of Ureter and Adjacent Tissue by Extravasation of Irrigation Fluid

Seoung, In Gi; Yoon, Jong Byung

Abstract

The study was designed to evaluate the radiological and pathological changes in the periureterally extravasated left ureter of rabbit following the irrigation with normal saline without dilatation and the effects of steroid in 30 rabbits. The rabbits were divided into two groups :the periureterally extravasated group without steroid administration( irrigation group) and the steroid administered group before and after ureteral irrigation( irrigation + steroid group). The results were as follows: 1. The frequency of ureteral peristalsis was decreased in both irrigation group and irrigation steroid group compared to the that of pre-irrigated one but with no significant difference between two groups. 2. The ureteric wall was easily liable to hydrostatic inflammatory reactions even with only periureteral extravasation in both irrigation group and irrigation +steroid group but with no significant difference between two groups. 3. The mechanism for the ureteral and periureteral fibrosis at an area where ureteroscope hasn't contacted is thought to be related to the microscopic or visible injury of transitional epithelium of ureter followed by extensive mucosal or periureteral extravasation of irrigation fluid resulted from high pressure of the irrigant within the ureteral lumen.