J Korean Acad Periodontol.  2002 Jun;32(2):325-337. 10.5051/jkape.2002.32.2.325.

The Comparative Study of Bone Grafts using Platelet Rich Plasma and Calcium Sulfate Barrier for the Regeneration of Infrabony Defects

• Kim KS
• Chung CH
• Lim SB

• KMID: 2057044
• DOI: http://doi.org/10.5051/jkape.2002.32.2.325

Abstract

Bone graft using growth factors and guided tissue regeneration have been used for the regeneration of infrabony defects which caused by periodontal disease. Calcium sulfate which is one of the resorbable barrier materials used for guided tissue regeneration. Platelet rich plasma which is a easy method to obtain the growth factors had many common points but, platelet rich plasma was still studying. This study was the comparative study between bone graft using platelet rich plasma and guided tissue regeneration using calcium sulfate barrier material in clinical view. For the study, 28 sites(2 or 3 wall infrabony defects) were treated. 14 infrabony defects were received surgical implantation of BBP-calcium sulfate composite with a calcium sulfate barrier and the others received BBP mixed with platelet rich plasma. Clinical outcome was accessed 3 and 6 months of postsurgery. 1. There was no statistical difference between CS group and PRP group in pocket depth, gingival recession, clinical attachment level, and probing bone level at baseline. 2. was statistically significant reduction in probing depth, clinical attachment level, and probing bone level at 3 and 6 months postsurgery(p<0.05). 3. In the probing depth and clincial attachment level PPR group had less improvement than CS group, but there was no statistically difference at 3 and 6 months postsurgery. 4. In the recession PPR group had less recession than CS group, but there was no statistically difference at 3 and 6 months postsurgery. 5. In the probing bone level PPR group had less improvement than CS group, but there was no statistically difference at 6 months postsurgery. In conclusion bone graft using platelet rich plasma and guided tissue regeneration using calcium sulfate barrier showed similar clinical improvement for the treatment of 2 or 3 wall infrabony defects.

MeSH Terms

Blood Platelets*
Calcium Sulfate*
Calcium*
Gingival Recession
Guided Tissue Regeneration
Intercellular Signaling Peptides and Proteins
Periodontal Diseases
Platelet-Rich Plasma*
Regeneration*
Transplants*
Calcium
Calcium Sulfate
Intercellular Signaling Peptides and Proteins