J Korean Acad Oral Maxillofac Radiol.  1997 Feb;27(1):203-216.

Radiation effect on the stages of amelogenesis in the rat incisor

• Choi HB
• Choi SC
• Park TW
• You DS

Abstract

The purpose of this study was to investigate the radiation effect on the stages of amelogenesis. Twenty 11-day-old rats which were irradiated by 4GY of gamma radiation on the 19th prenatal day were used for the experimental group and twenty 11-day-old rats which were not irradiated were used for the control group. The length of each zone of amelogenesi s were measured on the sagittal section using a light microscopic enlargement at 400 X the normal view while the morphol ogic changes of ameloblasts of each zone were observed electron-microscopically. The obtined results were as followed: 1. The length of the region of facing pulp and facing dentin of the zone of presecretion were increased by 11.5%(P<0.05) and 17.7%(P<0.01), respectively. 2. The length of the zone of secretion was increased by 17.3%(P<0.01), but the zone of maturation was decreased by 15.3%(P<0.01). 3. The total length of the zone of amelogenesis was not changed significantly(P>0.05). 4. Electron-microscopically, enlargement of the cell membrane, rER, mitochondria, and nuclear membrane were observed. These changes were mostly severe in the zone of maturation.

MeSH Terms

Ameloblasts
Amelogenesis*
Animals
Cell Membrane
Dentin
Gamma Rays
Incisor*
Mitochondria
Nuclear Envelope
Radiation Effects*
Rats*