Gut Liver.
2008 Dec;2(3):174-179.
Usefulness of Autofluorescence Imaging for Estimating the Extent of Gastric Neoplastic Lesions: A Prospective Multicenter Study
- Affiliations
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- 1Department of Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea.
- 2Department of Internal Medicine, Soon Chun Hyang University College of Medicine, Seoul, Korea.
- 3Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. choim@catholic.ac.kr
- 4Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea.
- 5Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
- 6Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
- 7Department of Internal Medicine, Kyung Hee University College of Medicine, Seoul, Korea.
- 8Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
- 9Department of Internal Medicine, Inje University Busan Paik Hospital, Busan, Korea.
Abstract
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BACKGROUND/AIMS: The aim of this study was to determine whether the margin of early to be detected gastric cancer (EGC) and gastric adenoma is easier to be detected with autofluorescence imaging (AFI) than with white-light endoscopy (WLE).
METHODS
A total of 102 lesions (48 EGCs and 54 gastric adenomas) found in 98 patients were removed endoscopically or surgically. The measured length of each pathology specimen was compared with the lengths estimated using WLE, AFI, and chromoendoscopy.
RESULTS
The lesions could be discriminated from surrounding mucosa by AFI in 86 cases (84.3%). The detection rates were similar for elevated lesions (85.1%) and flat/depressed lesions (82.9%, p=0.770). In terms of histology, the detection rate was slightly higher for adenomas (90.7%) than for cancer (77.1%, p=0.058). The estimated length was shorter than the pathologic length in 31.4% of cases when using WLE and 22.1% of cases when using AFI (p=0.168). The resection range was larger for EMR than for AFI in 24 of 80 cases (30.0%).
CONCLUSIONS
WLE tends to underestimate the size of EGCs, whereas AFI tends to overestimate their size.
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