Mycobiology.  2008 Mar;36(1):55-59. 10.4489/MYCO.2008.36.1.055.

Chemical Constituents of Gymnopilus spectabilis and Their Antioxidant Activity

• Lee IK
• Cho SM
• Seok SJ
• Yun BS

• KMID: 2052889
• DOI: http://doi.org/10.4489/MYCO.2008.36.1.055

Abstract

Gymnopilus spectabilis, a hallucinogenic mushroom belonging to the family Cortinariaceae, is found growing in dense clusters on stumps and logs of hardwoods and conifers. It contains the hallucinogenic alkaloid psilocybin and its strongly bitter taste makes it undesirable as an edible. In an effort to identify chemical constituents of Korean native wild mushrooms, 4,6-decadiyne-1,3,8-triol (1), ergosta-4,6,8(14), 22-tetraen-3-one (2), bisnoryangonin (3), and hispidin (4) were isolated from the methanolic extract of the fruiting bodies of G. spectabilis. Their structures were assigned on the basis of various spectroscopic studies. Compounds 3 and 4 displayed significant scavenging activity against the ABTS radical cation, DPPH radical, and superoxide radical anion, while 1 and 2 exhibited no antioxidant activity.

Keyword

Antioxidant; Bisnoryangonin; 4,6-Decadiyne-1,3,8-triol; Ergosta-4,6,8,22-tetraen-3-one; Gymnopilus spectabilis; Hispidin

MeSH Terms

Agaricales
Benzothiazoles
Coniferophyta
Fruit
Humans
Methanol
Pyrones
Sulfonic Acids
Superoxides
Benzothiazoles
Methanol
Pyrones
Sulfonic Acids
Superoxides