Korean J Hematol.  1997 Nov;32(3):476-480.

A Case of Cutaneous Extramedullary Hematopoiesis in Idiopathic Myelofibrosis

Affiliations
  • 1Department of Internal Medicine, Pusan National University Hospital, College of Medicine, Pusan, Korea.

Abstract

Idiopathic myelofibrosis is characterized by replacement of the bone marrow with fibrous tissue and the development of extramedullary hematopoiesis. The latter involves mainly the spleen and liver but also occurs in lymph nodes, kidneys, retroperitoneal fat, and more rarely, the skin. We report a 48-year-old male with idiopathic myelofibrosis who was admitted due to numerous papules and nodules on his trunk. The skin lesions were histologically defined as cutaneous extramedullary hematopoiesis.

Keyword

Extramedullary hematopoiesis; Dermis; Myelofibrosis

MeSH Terms

Bone Marrow
Dermis
Hematopoiesis, Extramedullary*
Humans
Intra-Abdominal Fat
Kidney
Liver
Lymph Nodes
Male
Middle Aged
Primary Myelofibrosis*
Skin
Spleen
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