Korean J Pediatr.  2009 Jan;52(1):129-132. 10.3345/kjp.2009.52.1.129.

Changes in N-terminal pro-B-type natriuretic peptide in a neonate with symptomatic isolated left ventricular noncompaction

• Song JH
• Kim YH
• Kim CS
• Lee SL
• Kwon TC

• KMID: 2037349
• DOI: http://doi.org/10.3345/kjp.2009.52.1.129

Abstract

We describe here our experience with a neonate presenting with cyanosis, grunting, and cardiome galy, who was diagnosed with isolated left ventricular noncompaction (IVNC) by echocardiography. The patient had high levels of N-terminal pro-B-type natriuretic peptide (NT pro-BNP) and symptoms of heart failure including poor feeding and tachypnea. During the period in which NT pro-BNP levels steadily increased, the patient suffered sudden cardiac arrest despite heart failure management. Following cardiopulmonary resuscitation, cardiac arrest was resolved, NT pro-BNP levels decreased, and all symptoms showed improvement. We consider that assessment of NT pro-BNP with cardiac functional analysis using echocardiography could help in the prediction of disease progress in IVNC.

Keyword

Newborn; Myocardium; Natriuretic peptide; Brain

MeSH Terms

Brain
Cardiopulmonary Resuscitation
Cyanosis
Death, Sudden, Cardiac
Echocardiography
Heart Arrest
Heart Failure
Humans
Infant, Newborn
Myocardium
Tachypnea