J Korean Geriatr Soc.
2005 Mar;9(1):15-22.
Clinical Implication of B-type Natriuretic Peptide in the Elderly
Abstract
- Brain natriuretic peptide (BNP) is one of natriuretic peptide hormones, a family of vasoactive peptides with many favourable phy- siological properties. It is released primarily from the cardiac ventricles in ! response to myocyte stretch and ischemia. It is synthesized as an inactive prohormone that is split into the active hormone and the inactive N-terminal fragment (NT-pro BNP). Recently, BNP has emerged as important candidates for diagnostic tools and therapeutic agents in cardiovascular disease. Here, we focus on the physiology of the natriuretic peptide system, measurement of circulating concentrations of BNP and the NT-pro BNP to diagnose heart failure, and to assess the prognosis in patients with cardiovascular disease.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Biomarkers in Heart Failure: Focus on B-type Natriuretic Peptide
- B-type natriuretic peptide may have a role in the management of patent ductus arteriosus
- B-type natriuretic peptide in anesthesia practice to predict adverse cardiovascular outcomes
- High Plasma Levels of the B-type Natriuretic Peptide in Patients Without Heart Failure: Is There Clinical Significance?
- Role of Brain Natriuretic Peptide as a Prognostic Marker in Non-Cardiac Surgery
