J Korean Radiol Soc.
2008 Jun;58(6):561-569. 10.3348/jkrs.2008.58.6.561.
Self-Expandable Polytetrafluoroethylene (PTFE)-covered Nitinol Stent for the Palliative Treatment of Malignant Biliary Obstruction
- Affiliations
-
- 1Department of Radiology, Gospel Hospital, College of Medicine, Kosin University, Korea. gsjung@medimail.co.kr
- 2Department of Radiology, Masan Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea.
- 3Department of Internal Medicine, Gospel Hospital, College of Medicine, Kosin University, Korea.
- 4Department of General Surgery, Gospel Hospital, College of Medicine, Kosin University, Korea.
- KMID: 2024535
- DOI: http://doi.org/10.3348/jkrs.2008.58.6.561
Abstract
- PURPOSE
We wanted to determine the technical and clinical efficacy of placing a self-expandable PTFE-covered nitinol stent for the management of inoperable malignant biliary obstruction.
MATERIALS AND METHODS
Thirty six patients with inoperable malignant biliary obstructions were treated by placement of self-expandable PTFE-covered nitinol stents (S & G Biotech Corporation, Seongnam, Korea). Clinical evaluation was done with assessment of the serum bilirubin and alkaline phosphatase levels, which were measured before and after stent placement within 1 week, at 1 month and at 3 months. The patient survival rate and stent patency rate were calculated with performing Kaplan-Meier survival analysis.
RESULTS
Successful stent placement was achieved in all the patients without procedure-related complication. Pancreatitis as an early complication occurred in two cases. The serum bilirubin and alkaline phosphatase levels were significantly decreased after the procedure. During the follow-up, recurrent obstructive jaundice occurred in six cases; stent migration occurred in four cases and tumor overgrowth occurred in two cases. The survival rates were 97%, 80%, 67% and 59% at 1, 3, 6 and 9 months, respectively. The stent patency rates were 96%, 92%, 86% and 86% at 1, 3, 6 and 9 months, respectively.
CONCLUSION
Self-expandable PTFE-covered nitinol stent placement seems to be technically feasible and effective for the palliative treatment of malignant biliary obstruction.
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