Korean J Dermatol.  2007 Dec;45(12):1311-1314.

A Case of Generalized Lichen Nitidus Treated with Low Dose Cyclosporine

• Lee YK
• Choi KW
• Kim YH
• Lee CW
• Kim KH

Abstract

Lichen nitidus is a rare and chronic inflammatory dermatosis first described by Pinkus in 1907. The etiology of it is still unknown and the majority of instances appear in children and young adults. The lesions are usually asymptomatic but may be mildly pruritic and the Koebner phenomenon may be observed. It is characterized by flesh-colored, minute, shiny papules occurring on the genitalia, abdomen, chest, and extremities. This disorder is most often localized, but there are rare reports of patients having a more generalized distribution of lesions. Although lichen nitidus is self-limited in most cases without any sequelae, the course of generalized lichen nitidus is unpredictable. We report a case of a 16-year-old girl diagnosed by generalized lichen nitidus refractory to general treatment and successfully treated with low dose cyclosporine (2 mg/kg/day).

Keyword

Generalized lichen nitidus; Low dose cyclosporine

MeSH Terms

Abdomen
Adolescent
Child
Cyclosporine*
Extremities
Female
Genitalia
Humans
Lichen Nitidus*
Lichens*
Skin Diseases
Thorax
Young Adult
Cyclosporine