Korean J Obstet Gynecol.  2006 Mar;49(3):667-673.

Two Cases of Pregnancies Complicated with Central Diabetes Insipidus

Affiliations
  • 1Deparment of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea. jsparkmd@snu.ac.kr
  • 2Seoul Municipal Boramae Hospital, Seoul, Korea.

Abstract

Diabetes insipidus is an unusual cause of urinary frequency during pregnancy. It occurs in 2 to 6 per 100,000 pregnancies. It is a disorder in which the abnormal secretion, degradation, or activity of vasopressin cause hypotonic polyuria, polydipsia, and dehydration. And this syndrome appears to be associated with multiple gestations, preeclampsia, and abnormal liver function. We report two cases of pregnancies complicated with diabetes insipidus. One patient was diagnosed during pregnancy and DDAVP (L-deamino-8-d-arginine vasopressin) was used to manage diabetes insipidus. The other patient was diagnosed before pregnancy and DDAVP was not used.

Keyword

Diabetes insipidus; Pregnancy

MeSH Terms

Deamino Arginine Vasopressin
Dehydration
Diabetes Insipidus
Diabetes Insipidus, Neurogenic*
Humans
Liver
Polydipsia
Polyuria
Pre-Eclampsia
Pregnancy*
Vasopressins
Deamino Arginine Vasopressin
Vasopressins
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