Korean J Pathol.  2012 Apr;46(2):197-200.

Parathyromatosis: Critical Diagnosis Regarding Surgery and Pathologic Evaluation

• Aksoy-Altinboga A
• Akder Sari A
• Rezanko T
• Haciyanli
• Orgen Calli A

Abstract

Parathyromatosis, in which several nodules of hyperfunctioning parathyroid tissue form in the neck and mediastinum, is a rare cause of recurrent hyperparathyroidism. However, there are some theories regarding the origin of parathyromatosis, and seeding after rupture of the parathyroid gland capsule during surgical removal of a parathyroid lesions is the most regarded one. Herein, we report a 41-year-old man who presented with multiple parathyroid nodules in and around the left thyroid lobe 5 years after parathyroid surgery for secondary hyperparathyroidism that was finally diagnosed as parathyromatosis. We discuss the differential diagnosis of parathyromatosis from other parathyroid tumors, particularly from parathyroid carcinoma, which is important in the management of a suspected lesion.

Keyword

Parathyromatosis; Parathyroid; Carcinoma; Adenoma

MeSH Terms

Adenoma
Adult
Diagnosis, Differential
Humans
Hyperparathyroidism
Hyperparathyroidism, Secondary
Mediastinum
Neck
Parathyroid Glands
Parathyroid Neoplasms
Rupture
Seeds
Thyroid Gland