Korean J Pathol.  1999 Jun;33(6):463-466.

Adrenocortical Oncocytoma: A case report

• Cha HJ
• Suh YL
• Yang JH

Abstract

Adrenal gland is a rare location for an oncocytic neoplasm. In English literature less than 10 cases of adrenocortical oncocytoma have been reported. We have experienced a case of adrenocortical oncocytoma in a 35-year-old man which was detected incidentally during the ultra-sonographic evaluation of the abdomen for a routine physical examination. This case did not demonstrate any clinical evidence of adrenocortical abnomalities, such as virilization or hypertension. Grossly, the tumor was light to dark tan on cut surface. Light-microscopic examination revealed tumor cells with abundant lipid- sparse eosinophilic cytoplasm and occasional pleomorphic nuclei. Mitotic figures were less than 5/50 HPFs. Tumor cells were positive for vimentin but negative for pancytokeratin, CAM 5.2, chromogranin and synaptophysin. Ultrastructural examination demonstrated abundant mitochondria containing occasional intramitochondrial dense bodies or inclusions.

Keyword

Adrenal cortical neoplasm; Oncocytoma; Intramitochondrial inclusion

MeSH Terms

Abdomen
Adenoma, Oxyphilic*
Adrenal Glands
Adult
Cytoplasm
Eosinophils
Humans
Hypertension
Mitochondria
Physical Examination
Synaptophysin
Triacetoneamine-N-Oxyl
Vimentin
Virilism
Synaptophysin
Triacetoneamine-N-Oxyl
Vimentin