Korean J Med.  2013 Apr;84(4):581-585.

Case of Incidental Oncocytic Adrenocortical Neoplasm

• Kim DH
• Sung JY
• Rhee SY
• Park SY
• Son JI
• Chin SO
• Chon S

Abstract

Adrenal oncocytomas are very rare. Because most of them are benign and nonfunctioning, they are detected incidentally. Here, we report a case of nonfunctioning benign adrenocortical oncocytoma located in the left adrenal gland in a 54-year-old man who presented with no symptoms. The tumor was 4.5 x 3 x 3 cm in size and was predominantly composed of oncocytes, which exhibited abundant eosinophilic granular cytoplasm and were arranged with a nested or diffuse architecture without capsular or vascular invasion. Nuclear atypia and mitotic figures were not observed. A discussion of this case and a review of recent updates in the literature are presented. In patients with adrenocortical oncocytomas, treatment is similar to that for adrenocortical neoplasia. However, due to the risk of over-diagnosis of malignancy, and the better clinical outcomes associated with adrenocortical oncocytoma, more attention should be paid to the diagnosis of adrenocortical oncocytoma.

Keyword

Adrenocortical adenoma; Oncocytoma; Oxyphil cells

MeSH Terms

Adenoma, Oxyphilic
Adrenal Glands
Adrenocortical Adenoma
Cytoplasm
Eosinophils
Humans
Oxyphil Cells