J Korean Child Neurol Soc.  1999 Dec;7(2):228-236.

Intracranial Hemorrhage in Late Hemorrhagic Disease of the Newborn: Brain Computed Tomographic Findings

• Yoon CS
• Park JG
• Kim MJ
• Park MS
• Park KI
• Lee JS

Abstract

PURPOSE: This study is to evaluate the Brain CT manifestations of late hemorrhagic disease of the newborn.
METHODS
We evaluated 13 cases with late hemorrhagic disease of the newborn, for whom brain CT scans were performed. Clinical indications for brain CT scan were mental changes(n=5), vomiting(n=2), irritability(n=2), seizure(n=3), and lethargy(n=1). We analyzed the result of the brain CT findings with attention to anatomic locations of hemorrhage and characteristics of hemorrhagic manifestations.
RESULTS
Only one patient in 13 patients was normal on brain CT scan, and 12 patients showed hemorrhagic lesions. Among 12 patients, 5 cases had single hemorrhagic lesion(3 subdural hemorrhages and 2 intracerebral hemorrhages, and 7 cases had multiple lesions, in which subdural hemorrhage and subarachnoid hemorrhage were common respectively. The other common brain CT findings except hemorrhagic lesion were the mass effects with ventricle compression(n=11), midline shifting(n=6), ventricular dilatation(n=7), and fluid-fluid levels in hemorrhagic lesion(n=9).
CONCLUSION
The common intracranial hemorrhages of late hemorrhagic disease of the newborn were subdural and subarachnoid hemorrhages. The associated CT findings were mass effect and fluid-fluid levels. Intracranial hemorrhage in late hemorrhagic disease of newborn could massively occurr. Thus brain CT scan should be done if any symptom for neurologic abnormality was present.

Keyword

Hemorrhagic disease; Newborn; Intracranial Hemorrhage; Brain CT scan

MeSH Terms

Brain*
Cerebral Hemorrhage
Hematoma, Subdural
Hemorrhage
Humans
Infant, Newborn*
Intracranial Hemorrhages*
Subarachnoid Hemorrhage
Tomography, X-Ray Computed
Vitamin K Deficiency Bleeding