J Korean Pediatr Soc.
1980 Jul;23(7):572-577.
Late Hemorrhagic Disease of Infancy
- Affiliations
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- 1Dept. of Pediatrics, College of Medicine, Seoul National University, Korea.
Abstract
- A hemorrhagic disease due to prothrombin complex deficiency os described in 4 infants from 1 to 11 months of age. This disease is different from the hemorrhagic disease of the newborn. The main differences are that it is found in an older age group and that intracranial hemorrhages are frequent. Rapid clinical and laboratory response after vitamin K therapy are observed. Severe prothrmbin complex deficiency due to vitamin K deficiency is a accounted for the pathogenesis of bleeding. Possible causes of vitaimn K deficiency are reviewed.
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