J Korean Soc Pediatr Endocrinol.  2000 Dec;5(2):210-214.

A Case of Neonatal Diabetes Mellitus: Transient or Permanent?

Abstract

A case of neonatal diabetes mellitus is described. The child presented with low birth weight but was normal in appearance. She was acidotic and ketonuria was observed. The HLA typing was DR1 and 3, and insulin autoantibodies were negative. Genetic analysis with polymorphic DNA markers for chromosome 6 indicated biparental inheritance. She required insulin therapy for the control of hyperglycemia, and insulin dependence continues after 8 months of age.

Keyword

Neonatal diabetes mellitus; Polymorphic DNA marker; Chromosome 6; Biparental inheritance

MeSH Terms

Autoantibodies
Child
Chromosomes, Human, Pair 6
Diabetes Mellitus*
Genetic Markers
Histocompatibility Testing
Humans
Hyperglycemia
Infant, Low Birth Weight
Infant, Newborn
Insulin
Ketosis
Wills
Autoantibodies
Genetic Markers
Insulin
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