Korean J Nephrol.
2004 Jan;23(1):158-162.
Two Cases of FSGS Maintaining Renal Function by Long Term Cyclosporine Treatment
- Affiliations
-
- 1Department of Internal Medicine, College of Medicine, Chungbuk National University, Cheongju, Korea.
- 2Department of Internal Medicine, College of Medicine, Ulsan University, Seoul, Korea. skpark@amc.seoul.kr
Abstract
- Cyclosporine can cause remission of 60% in steroid resistant FSGS, but its responses are variable. Now we report two cases of steroid resistant FSGS who are maintaining remission using cyclosporine continuous therapy. The first patient had been failed several times of steroid therapy, had edema, azotemia and severe proteinuria. We used steroid pulse therapy then maintenance dose of oral cyclosporine to reduce proteinuria for more than 6 years. He has been received cyclosporine therapy up to now and maintaining normal renal function. The second patient had severe azotemia who needed hemodialysis but after cyclosporine therapy, he recovered his renal funciton. The findings of renal biopsies in one patient after 6 years of cyclosporine therapy revealed that there was no improvement of sclerosing glomeruli, then we guess that maintenance therapy of cyclosporine might need for lifelong period.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Plasmapheresis in Recurrent Focal Segmental Glomerulosclerosis after Renal Transplantation
- Prevention of Recurrent FSGS with Cyclosporine and Plasmapheresis Prior to Renal Transplantation
- Therapeutic response of cyclosporine and outcome in steroid resistant nephrotic syndrome
- Second Trial of Cyclosporin A-Induced Remission in Other Immunosuppressant Therapy-Resistant FSGS Patient
- Long-term Prognostic Factors in Pediatric Focal Segmental Glomerulosclerosis
