Korean J Dermatol.
2003 Dec;41(12):1638-1643.
A Case of Aggressive T/NK-cell Lymphoma/leukemia with Cutaneous Involvement
- Affiliations
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- 1Department of Dermatology, Jeju National University, College of Medicine, Jeju, Korea. rulidroxim@hanmail.net
- 2Department of Dermatology, Hallym University, College of Medicine, Seoul, Korea.
Abstract
- Non-nasal T/NK-cell lymphomas(TNKCL) are further subdivided into primary cutaneous and 4 subtypes of secondary cutaneous lymphomas such as nasal type, aggressive, blastic(blastoid), and other specific NK-like T-cell lymphoma. Aggressive T/NK-cell lymphoma/leukemia(ATNKCL) is a rare leukemic variant of nasal type TNKCL. Although ATNKCL invariably exhibits the identical histomorphological, genotypical and immunophenotypical findings with TNKCL, it is distinguishable from the nasal type of TNKCL in that the former reveals atypical cells having large azurophilic cytoplasmic granules in the peripheral blood and bone marrow. We herein report a rare case of ATNKCL with secondary cutaneous lesions.
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