Anesth Pain Med.  2010 Jul;5(3):255-259.

Effects of acetaminophen on postoperative emergence delirium in children undergoing epiblepharon correction

Affiliations
  • 1Department of Anesthesiology and Pain Medicine, Dong-A University Hospital, Busan, Korea. yjjin@dau.ac.kr

Abstract

BACKGROUND
Emergence delirium is a common problem after general anesthesia in children. Postoperative pain control reduces the incidence of emergence delirium. Opioids and NSAIDs have been successfully used to inhibit intraoperative and postoperative pain. Instead of them, acetaminophen is used to reduce side effects of opioids and NSAIDs. This study evaluated the effect of acetaminophen on emergence delirium after general anesthesia in children undergoing a epiblepharon correction.
METHODS
Sixty children, aged 1-10 years (ASA physical status I, II) undergoing epiblepharon correction, were enrolled in this study. Acetaminophen (group A) received 15 mg/kg of acetaminophen, control group (group C) received 1.5 ml/kg of normal saline. Anesthesia was induced with 2.0 mg/kg of ketamine and maintained by 2.0-3.0 vol% sevoflurane with N2O 1.5 L/min-O2 1.5 L/min. The delirium score was recorded at 10 minutes after arrival at recovery room by an independent observer using the four point scale of Aono.
RESULTS
There were no significant differences between the two groups regarding the time to extubation and discharge from the recovery room. The incidence of emergence delirium was 23% in group A and 32% in group C, but this did not have statistical significance. The incidence of vomiting was similar in both group.
CONCLUSIONS
Preoperative intravenous acetaminophen of 15 mg/kg application does not reduce the incidence of postoperative delirium in children undergoing epiblepharon correction.

Keyword

Acetaminophen; Pediatric anesthesia; Postoperative delirium

MeSH Terms

Acetaminophen
Aged
Analgesics, Opioid
Anesthesia
Anesthesia, General
Anti-Inflammatory Agents, Non-Steroidal
Child
Delirium
Humans
Incidence
Ketamine
Methyl Ethers
Pain, Postoperative
Recovery Room
Vomiting
Acetaminophen
Analgesics, Opioid
Anti-Inflammatory Agents, Non-Steroidal
Ketamine
Methyl Ethers
Full Text Links
  • APM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr