J Korean Assoc Maxillofac Plast Reconstr Surg.  2012 May;34(3):220-225.

Osteonecrosis of Maxilla in Wegener's Granulomatosis: Case Report

• Kim IK
• Chang JW
• Ju SH
• Pyeon YH
• Jung BS
• Han JY

Abstract

Wegener's granulomatosis (WG) is an autoimmune disease of unknown etiology characterized by the triad of necrotizing granulomatous lesion in the upper and lower respiratory tracts or both, disseminated vasculitis involving both small arteries and veins, and necrotizing glomerulonephritis. The most common oral lesions associated with WG are ulceration and strawberry gingivitis. A 47-years old man in medical care associated WG was consulted our Division of Oral and Maxillofacial Surgery for the chief complaint of toothaches. Pre-operative panorama showed the alveolar radiolucency and the loss of lamina dura regarding the left upper teeth. An oropharyngeal magnetic resonance imaging also revealed the increased bone marrow signal intensity on the left maxilla. Under the impression of maxillary osteonecrosis due to WG, maxillary saucerization with removal of involved teeth was performed. We obtained good results and report the first case of WG in Korea, with the review of literatures regarding oral and general systemic features.

Keyword

Osteonecrosis; Wegener's granulomatosis; Maxilla

MeSH Terms

Arteries
Autoimmune Diseases
Bone Marrow
Fragaria
Gingivitis
Glomerulonephritis
Korea
Magnetic Resonance Imaging
Maxilla
Osteonecrosis
Respiratory System
Surgery, Oral
Tooth
Toothache
Ulcer
Vasculitis
Veins
Wegener Granulomatosis