Ewha Med J.  2001 Sep;24(3):131-135. 10.12771/emj.2001.24.3.131.

A Case of Infectious Mononucleosis

Affiliations
  • 1Department of Internal Medicine, College of Medicine, Ewha Womans University, Korea.

Abstract

Infectious mononucleosis is an acute lymphoproliferative disease that is most common in children and young adults and is caused by Epstein-Barr virus. Characteristic clinical feastures include : 1) fever, sore throat, and lymphadenopathy ; 2) an associated absolute lymphocytosis greater than 50%, of which at least 10% are atypical lymphocytes in the peripheral blood ; 3) development of transient heterophil and persistent antibody responses against Epstein-Barr virus ; and 4) abnormal liver function tests. The most prevalent age of infectious mononucleosis in Korea was less than 5 years old and it has been very rare in adulthood. However, recently in Korea, possibly due to the increasing number of people who are non-immune to Epstein-Barr virus, the age range seems to be increasing from young childhood to over 10 years old and even to adulthood. We present a 19-year-old man who showed typical clinical features of infectious mononucleosis.

Keyword

Infectious mononucleosis; Epstein-Barr virus

MeSH Terms

Antibody Formation
Child
Fever
Herpesvirus 4, Human
Humans
Infectious Mononucleosis*
Korea
Liver Function Tests
Lymphatic Diseases
Lymphocytes
Lymphocytosis
Pharyngitis
Young Adult
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