J Korean Assoc Maxillofac Plast Reconstr Surg.  2006 Jan;28(1):80-86.

Treatment of a patient with cleidocranial dysplasia using implant-supported bar overdenture: a case report

• Jang JH
• Song MS
• Kim HM
• Kim NH
• Eom MY
• Koo HM
• Yi JK
• Jeong JC
• Kim SW

Abstract

Cleidocranial dysplasia is rare inherited skeletal dysplasia. It was first reported by Martin in 1765. Subsequently, Marie and Sainton independently documented the criteria of the disease. Cleidocranial dysplasia is a bone disorder caused by a defect in the CBFA1 gene of chromosome 6p21. This gene guides osteoblastic differentiation and appropriate bone formation. Patient with cleidocranial dysplasia has maxillary deficiency, high and narrow palate, prolonged retention of primary teeth, unerupted permanent teeth and supernumerary teeth. Therapeutic options in these patients include of autotransplantation of selected impacted teeth, forced eruption of permanent teeth, full denture, overdenture and implant-supported prosthesis. We report a patient with cleidocranial dysplasia. This patient was treated with implant supported bar overdenture. Despite of gene defect that affects osteoblastic activity, bone remodeling and osseointegration occurred in our patient. So, we report this case with review of literature.

Keyword

Cleidocranial dysplasia; Overdenture; Impacted tooth; Implant

MeSH Terms

Autografts
Bone Remodeling
Cleidocranial Dysplasia*
Denture, Overlay*
Dentures
Humans
Orthodontic Extrusion
Osseointegration
Osteoblasts
Osteogenesis
Palate
Prostheses and Implants
Tooth
Tooth, Deciduous
Tooth, Impacted
Tooth, Supernumerary