J Korean Pain Soc.  1994 Nov;7(2):299-302.

Extravasation of Prostaglandin E1 during Bier Block for the Treatmtent of Occlusive Arterial Disease

• Choe H
• Lee YT
• Kim DC
• Han YJ

Abstract

Prostaglandin El (PGEl) is a potent vasodilator and is a useful drug for the treatment of occlusive peripheral vascular disease. It has been used systemically via intravenous route or regionally via intraarterial route. We tried intravenous regional administration of PGEl for the treatment of a patient with occlusive arterial disease involving left fingers. During the l3th injection, the patient complained of severe pain at the injection site during the drug administration. Thereafter, the patient developed painful and severe swelling with blebs on his left hand. Systemic antibiotics were given together with stellate ganglion block of the affected left side. PGE1 was substituted to reserpine, which is subcutaneously injectable, for the second term treatment.

Keyword

Occlusive arterial disease; Prostaglandin E1; Intravenous regional block; Extravasation

MeSH Terms

Alprostadil*
Anti-Bacterial Agents
Blister
Fingers
Hand
Humans
Peripheral Vascular Diseases
Reserpine
Stellate Ganglion
Alprostadil
Anti-Bacterial Agents
Reserpine