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Reserpine treatment activates AMP activated protein kinase (AMPK)

Park R, Lee KI, Kim H, Jang M, Ha TK, Oh WK, Park J

Reserpine is a well-known medicine for the treatment of hypertension, however the role of reserpine in cell signaling is not fully understood. Here, we report that reserpine treatment induces the...
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Efflux Pump Inhibitor Carbonyl Cyanide-m-chlorophenylhydrazone (CCCP) Enhances Bacteriostatic Activity of Trimethoprim-sulfamethoxazole Against Clinical Stenotrophomonas maltophilia Isolates from Korea

Rhee JY, Choi JY, Ko KS

Although trimethoprim-sulfamethoxazole (TMP-SXT) is considered the first-line therapy for Stenotrophomonas maltophilia infections, there is debate on the use of the bacteriostatic drug in serious infections, and recently, there has been...
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Preventive Effect of Polysaccharide of Larimichthys crocea Swim Bladder on Reserpine Induced Gastric Ulcer in ICR Mice

Li GJ, Sun P, Wang R, Zhou YL, Qian Y, Zhao X

This project's aim was to determine the reserpine-induced gastric ulcer preventive effect of polysaccharide of Larimichthys crocea swim bladder (PLCSB) in ICR mice. The anti-gastric ulcer effects of polysaccharide of...
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Efflux-mediated resistance identified among norfloxacin resistant clinical strains of group B Streptococcus from South Korea

Dang TN, Srinivasan U, Britt Z, Marrs CF, Zhang L, Ki M, Foxman B

OBJECTIVES: Group B Streptococcus (GBS), a common bowel commensal, is a major cause of neonatal sepsis and an emerging cause of infection in immune-compromised adult populations. Fluoroquinolones are used to...
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Altered expression of gamma-secretase components in animal model of major depressive disorder induced by reserpine administration

Lee HR, Hwang IS, Kim JE, Choi SI, Lee YJ, Goo JS, Lee EP, Choi HW, Kim HS, Lee JH, Jung YJ, Hwang DY

Altered expression of neurotrophic factors as well as neuroinflammation is commonly associated with Major depressive disorder (MDD) and Alzheimer's disease (AD). To investigate whether or not reserpine-induced MDD affects the...
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The Effects of alpha-Adrenergic Drugs on the Myocardial Preconditioning in Rats

Jang WC, Song SY, Oh SG, Ahn BH, Kim SH

  • KMID: 1915691
  • Korean J Thorac Cardiovasc Surg.
  • 2001 Nov;34(11):809-822.
BACKGROUND: Ischemic preconditioning(IP) is known to be effective in the protection of myocardial necrosis, arrhythmia, and the restoration of the myocardial function in the ischemia-reperfusion state of the heart. However...
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Decreased expression of aquaporin-2 water channels in the kidney in rats treated with reserpine

Lee JU, Oh YW, Kim S

  • KMID: 2071570
  • Korean J Physiol Pharmacol.
  • 2001 Aug;5(4):307-313.
Whether there exists a Sympathetic neural mechanism regulating the expression of aquaporin (AQP) water channels in the kidney was investigated. Male Sprague-Dawley rats were treated with reserpine (1 mg/kg, IP), and the expression...
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The effect of treatment with tryptophan and/or reserpine on the serotonergic immunoreactivity in raphe nucleus of medulla oblongata and midbrain of the rats

Kim MS, Lee CH

  • KMID: 2030737
  • Korean J Anat.
  • 2001 Feb;34(1):33-40.
The present study was carried out to investigate the effect of treatment with tryptophan and/or reserpine on the raphe of medulla oblongata and mid brain of the rats (180~200 g...
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Intravenous Regional Block of Bretylium: Treatment of Reflex Sympathetic Dystrophy

Kim SK, Cho YR, Shin KM, Hong SY, Choi YR, Kim KM, Moon JS

BACKGROUND: Interruption of efferent sympathetic fibers is the mainstay of therapy in reflex sympathetic dystrophies(RSD) and be accomplished by temporary or permanent anesthetic blockade of sympathetic ganglia, surgical lesions of...
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Effect of Chemical Sympathectomy and Laser Radiation in the Neuropathic Pain

Hwang WJ, Kim MS, Lee WH

BACKGROUND: Treatments of neuropathic pain were included Ca blocker, steroid medication, epidural or spinal local anesthetics, intravenous reserpine and phenoxybenzamine and operative sympathectomy. This study was performed to evaluation the...
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Effect of Ischemic Preconditioning on Catecholamine Release from the Isolated, Ischemic Reperfused Hearts of Rats

Park JW, Kim YH, Kim MS

BACKGROUND: Ischemic preconditioning reduces the infarct size and the severity of arrhythmia in a post-ischemic reperfused heart although the detailed mechanism is unknown. In the ischemic heart, a large amount...
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Extravasation of Prostaglandin E1 during Bier Block for the Treatmtent of Occlusive Arterial Disease

Choe H, Lee YT, Kim DC, Han YJ

  • KMID: 1946512
  • J Korean Pain Soc.
  • 1994 Nov;7(2):299-302.
Prostaglandin El (PGEl) is a potent vasodilator and is a useful drug for the treatment of occlusive peripheral vascular disease. It has been used systemically via intravenous route or regionally...
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Effects of octreotide on the contractility of isolated rat vas deferens

Jang SA, Kwon OC, Ha JH, Lee KY, Kim WJ

This study was performed to investigate the effect of octreotide on the contractility of rat vas deferens. The -smooth muscle strips isolated from the prostatic portion were myographied in isolated...
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Inhibitory of γ-aminobutyric acid on the contractility of isolated rat vas deferens

Ahn KY, Kwon OC, Ha JH, Lee KY, Kim WJ

GABA is an inhibitory neurotransmitter in central nervous system and produce sedative, antianxiety and muscle relaxing effects via GABA(A) receptor or GABA(B) receptor. Recently it is known that GABA is...
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Efficacy of Repeated Subarachnoid Blocks in the Treatment of Reflex Sympathetic Dystrophy

Kim HD, Song SO, Kim SY

Reflex sympathetic dystrophy is a common posttraumatic pain syndrome for which no relia- bly effective method of therapy has been found. Oral therapy has been attempted with steroid, tricyclic antidepressant,...
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Intravenous Regional Administration of Prostaglandin E1 for the Treatment of Buerger's Disease

Choe H, Kim DC, Han YJ

  • KMID: 1946585
  • J Korean Pain Soc.
  • 1992 May;5(1):85-88.
Buerger's disease is a chronic occlusive arterial disease in which a non-arteriosclerotic lesion involves medium-sized arteries, veins, and nerves of the distal leg or arm. Sympathetic interruption is indicated to...
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A Study on the Role of Catecholamine in Reperfusion Damage of Ischemic Heart in Rat : Effect on Xanthine Oxidase Conversion

Kim MS, Yoo HJ, Chung MH, Lim JK, Lee YS

The present study was performed to investigate the role catecholamine in the genesis of reperfusion injury of ischemic heart. The possible involvement of catecholamine in the xanthine oxidase-linked production of...
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Finger Necrosis Resulting from Inadvertent Arterial Injection of Antibiotic

Choi KT, Kim JM, Cheun JK

  • KMID: 2104659
  • J Korean Pain Soc.
  • 1988 Dec;1(2):211-213.
Efforts from many different approaches have been made to cure Raynaud's phenomenon using dosal sympathectomy and topical injection of nitroglycerine, phentolamine or procaine and oral or parenteral administration of various...
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Intra-arterial Administration of Reserpine and Procaine with Stellate Ganglion Block for Raynaud's Phenomenon

Jeon JK, Chung JG, Choi KT, Song SO

  • KMID: 1946633
  • J Korean Pain Soc.
  • 1988 Jun;1(1):16-19.
Efforts from many different approaches have been made to cure Raynaud's phenomenon, such as a dorsal sympathectomy, topical injection of nitroglycerin, phentolamin and procaine, and oral or parentral administration of...
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Studies on Experimental Vasospasm: Effect of Reserpine on Experimental Vasospasm

Jun HK, Chung HS, Lee HK

  • KMID: 2187617
  • J Korean Neurosurg Soc.
  • 1988 Feb;17(1):19-28.
Preliminary in vitro experiments were performed to define the contraction effects of the serotonin and prostaglandin F2 alpha in cat's internal carotid artery. Subsquently 12 cats were used to study...
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