J Korean Pediatr Soc.  2001 Jul;44(7):823-826.

A Case of Aseptic Meningitis Following Administration of Intravenous Immunoglobulin in A Patient with Idiopathic Thrombocytopenic Purpura

Affiliations
  • 1Department of Pediatrics, College of Medicine, Dongguk University, Kyung-ju, Korea.
  • 2Department of Pediatrics, College of Medicine, The Catholic University of Korea, Taegu, Korea.

Abstract

Intravenous immunoglobulin(IVIG) has been widely used to treat idiopathic thrombocytopenic purpura in childhood. Aseptic meningitis has been reported as a rare complication of IVIG therapy. This report is on an 11 year-old boy with ITP who suffered from aseptic meningitis following the administration of IVIG. He was given 1 g/kg of IVIG for 2 days, and on the fourth day after the administration of IVIG, he experienced headache, vomiting and fever. Cerebrospinal fluid showed 400/mm3 white cells with 96% segmented neutrophils and 1% lymphocytes. The symptoms subsided within 8 days of admission.

Keyword

Intravenous immunoglobulin; Aseptic meningitis

MeSH Terms

Cerebrospinal Fluid
Child
Fever
Headache
Humans
Immunoglobulins*
Immunoglobulins, Intravenous
Lymphocytes
Male
Meningitis, Aseptic*
Neutrophils
Purpura, Thrombocytopenic, Idiopathic*
Vomiting
Immunoglobulins
Immunoglobulins, Intravenous
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