Korean J Anesthesiol.  1988 Dec;21(6):882-888. 10.4097/kjae.1988.21.6.882.

The Effects of Vecuronium on Hemodynamics and Intracranial Pressure in Cats

• Lee KC
• Park PH
• Suh BT

• KMID: 1933069
• DOI: http://doi.org/10.4097/kjae.1988.21.6.882

Abstract

We studied the cardiovascular and intracranial pressure(ICP) effects of Vecuronium in cats with normal and artificially increased ICP. Under pentobarbital and nitrous oxide anesthesia, monitors for ICP, Mean Arterial Pressure(MAP), Heart Rate(HR), and Central Venous Pressure(CVP) were placed in the cats. The cats were then divided into two groups: one with normal ICP( N-ICP) (n=8) and the other with artificially increased ICP (AI-ICP) (n=8). In the AI-ICP group, a size 8F Foley catheter was placed in the epidural space through a 5 mm trephined hole on the right parietal area. In each group, ICP, MAP, HR, CVP, and Cerebral Perfusion Pressure(CPP) were measured after Vecuronium injection(80ug/kg)(CPP=MAP-ICP). Results showed no statistically significant changes in cats with N-ICP and AI-ICP.

Keyword

Vecuronium; Intracranial pressure(ICP)

MeSH Terms

Anesthesia
Animals
Catheters
Cats*
Epidural Space
Heart
Hemodynamics*
Intracranial Pressure*
Nitrous Oxide
Pentobarbital
Perfusion
Rabeprazole
Vecuronium Bromide*
Nitrous Oxide
Pentobarbital
Vecuronium Bromide