Korean J Med.  2004 Nov;67(Suppl 3):S740-S745.

Two cases of isolated pulmonary valve infective endocarditis complicating ventricular septal defect

• Kim MA
• Lee HC
• Park SS
• Jung SM
• Lim DS
• Hong SK
• Baek MJ

Abstract

Isolated infective endocarditis in the native pulmonary valve is an unusual clinical entity in non-intravenous drug users. Intravenous drug abuse, alcoholism, sepsis, catheter related infections and congenital heart diseases account for the majority of predisposing factors. We report two cases of isolated pulmonary valve infective endocarditis complicating ventricular septal defect (VSD). A 43 year-old male was admitted because of mild fever, pansystolic murmur on the left lower sternal border. Transthoracic and transesophageal echocardiography revealed a large perimembranous ventricular septal defect and vegetations at the pulmonary valve. After the intravenous use of penicillin and gentamicin, patch closure of VSD with resection of vegetations, resection of anomalous muscle bundles on the right ventricle outlet tract and pulmonary valvuloplasty was performed. A 43 year-old female was admitted with spiking fever, dyspnea. Transthoracic and transesophageal echocardiography showed a small perimenbranous ventricular septal defect with pulmonary valve vegetations. Intravenous penicillin and gentamicin were continued for 4 weeks and she is doing well.

Keyword

Infective endocarditis; Pulmonary valve; Ventricular septal defect

MeSH Terms

Adult
Alcoholism
Catheter-Related Infections
Causality
Drug Users
Dyspnea
Echocardiography, Transesophageal
Endocarditis*
Female
Fever
Gentamicins
Heart Diseases
Heart Septal Defects, Ventricular*
Heart Ventricles
Humans
Male
Penicillins
Pulmonary Valve*
Sepsis
Substance Abuse, Intravenous
Gentamicins
Penicillins