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Epigenetic Regulation of Filaggrin Gene Expression in Human Epidermal Keratinocytes

Lee J, Jang A, Seo SJ, Myung SC

BACKGROUND: Loss-of-function mutations in the filaggrin gene (FLG), which encodes an epidermal protein crucial for the formation of a functional skin barrier, have been identified as a major predisposing factor...
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A Man Presenting with Sudden Weakness and Pain of the Right Hand, by Non-Small Cell Lung Cancer with Brain Metastases

Sung WJ, Hong BY, Kim JS, Yoo JW, Lim SH

Unexplained pain and weakness, i.e., without obvious predisposing factors, are often encountered by physiatrists and efforts should be made to determine the cause. A 63-year-old male presented with radiating pain...
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Acquired Periungual Fibrokeratoma: An Atypical Case Covering the Entire Thumb Nail

Ryu JY, Park CJ, Lee KH

  • KMID: 2470215
  • Korean J Dermatol.
  • 2019 Dec;57(10):617-620.
Acquired periungual fibrokeratoma, first reported by Cahn in 1977, is a rare, benign fibrous tissue tumor located in the periungual area. The pathophysiology of acquired periungual fibrokeratoma is unknown. In...
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Inferior turbinate outfracture for successful nasotracheal intubation in a patient undergoing maxillofacial surgery: case report

Kwon MA

An enlarged inferior turbinate is a predisposing factor for difficult nasotracheal intubation. We describe a case of successful nasotracheal intubation by induced outfracture of the inferior turbinate during maxillofacial surgery,...
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Relapsed Leprosy with Multiple Ulcerative Skin Lesions: A Case Report

Jeong HH, Hong SG, Park JM, Kim JP, Heo EP, Go JW

Leprosy is a chronic infectious and granulomatous disease caused by Mycobacterium leprae. It is treated with a multidrug therapy (MDT), which is consisted of dapsone, rifampicin, and clofazimine. However, there...
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Recurrent Kaposi Varicelliform Eruption: Investigation of Clinical Characteristics and Predisposing Factors

Bae KN, Kim T, Park S, Lee HJ, Jin H, You H, Shim WH, Kim GW, Kim HS, Ko HC, Kim BS, Kim MB

  • KMID: 2465916
  • Korean J Dermatol.
  • 2019 Nov;57(9):519-526.
BACKGROUND: Kaposi varicelliform eruption (KVE) is a disseminated viral infection primarily caused by the herpes simplex virus in the setting of an underlying chronic skin disease. Few studies have reported...
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Clinical Analysis of Bacterial Keratitis According to Culture Positivity

Kim D, Cho CH, Lee SB

PURPOSE: The purpose of this study was to evaluate the clinical aspects of inpatients with bacterial keratitis according to culture positivity. METHODS: This was a retrospective review of 98 cases of...
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Thoracic Posture and Mobility in Mechanical Neck Pain Population: A Review of the Literature

Joshi S, Balthillaya G, Neelapala

Neck pain is a common condition with several proposed biomechanical contributing factors. Thoracic spine dysfunction is hypothesized as one of the predisposing factors, which necessitates the need to explore the...
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Demographic and Socioeconomic Factors for Renouncing Further Active Therapy for Patients with Brain Metastasis of Non-Small Cell Lung Cancer

Jung G, Kim SH, Kim TG, Kim YZ

BACKGROUND: As patients with brain metastasis (BM) of non-small cell lung cancer (NSCLC) have dismal prognosis, some of them decide to discontinue further treatment for BM. The objective of this...
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Clinical Analysis of Staphylococcus Keratitis According to Coagulase Positivity

Choi N, Cho CH, Lee SB

PURPOSE: To analyze clinical aspects in a cohort of patients with Staphylococcus keratitis according to coagulase positivity (coagulase negative Staphylococcus [CNS], coagulase positive Staphylococcus [CPS]). METHODS: Epidemiology, predisposing factors, clinical characteristics,...
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Secondary Cervicothoracic Scoliosis in Congenital Muscular Torticollis

Kim JH, Yum TH, Shim JS

BACKGROUND: Although secondary cervicothoracic scoliosis frequently occurs in patients with congenital muscular torticollis (CMT), the relationship between scoliosis and CMT has not been evaluated. This study aims to evaluate the...
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The roles of triglyceride/high-density lipoprotein cholesterol ratio and uric acid as predisposing factors for metabolic syndrome in healthy children

Katsa ME, Ioannidis , Sachlas A, Dimopoulos I, Chatzipanagiotou S, Rojas Gil

PURPOSE: To estimate the roles of triglyceride/high-density lipoprotein cholesterol (TG/HDL) ratio and uric acid in predisposition for metabolic syndrome (MetS) and its components in healthy children. METHODS: Anthropometric and biochemical analyses...
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Usefulness of Carbohydrate Antigen 19-9 Test in Healthy People and Necessity of Medical Follow-up in Individuals with Elevated Carbohydrate Antigen 19-9 Level

Lee SP, Sung IK, Kim JH, Lee SY, Park HS, Shim CS

BACKGROUND: Carbohydrate antigen 19-9 (CA 19-9) is a tumor marker whose level is elevated in many types of cancers and other benign conditions. CA 19-9 levels are frequently found to...
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Predisposing factors for external apical root resorption associated with orthodontic treatment

Fernandes , Figueiredo NC, Montalvany Antonucci CC, Lages EM, Andrade I, Capelli Junior J

OBJECTIVE: This study aimed to identify possible risk factors for external apical root resorption (EARR) in the maxillary incisors after orthodontic treatment. METHODS: The root length of 2,173 maxillary incisors was...
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Investigation of the association of idiopathic male infertility with polymorphisms in the methionine synthase (MTR) gene

Tanoomand , Hajibemani A, Abouhamzeh B

OBJECTIVE: Spermatogenesis is a complex process that is regulated by a number of genes, some of which are involved in folate-dependent 1-carbon metabolism. Methionine synthase (encoded by MTR) is a...
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Comparison of Clinical Features according to FLG Mutation in Korean Atopic Dermatitis Patients

Lee H, Wang HY, Lee H, Choi EH

  • KMID: 2457686
  • Korean J Dermatol.
  • 2019 Aug;57(7):363-370.
BACKGROUND: Mutation in the gene encoding filaggrin (FLG) is a major predisposing factor for atopic dermatitis (AD), in association with distinct features such as increased allergic sensitization, higher severity, and...
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Designing and Evaluating Educational Intervention to Improve Preventive Behavior Against Cutaneous Leishmaniasis in Endemic Areas in Iran

Ghodsi M, Maheri M, Joveini H, Rakhshani , Mehri A

OBJECTIVES: Health education programs are one of the most important strategies for controlling cutaneous leishmaniasis (CL) in endemic areas such as Neshabur city. This study aimed to develop and evaluate...
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Lipid emulsion therapy of local anesthetic systemic toxicity due to dental anesthesia

Rhee SH, Park SH, Ryoo SH, Karm MH

Local anesthetic systemic toxicity (LAST) refers to the complication affecting the central nervous system (CNS) and cardiovascular system (CVS) due to the overdose of local anesthesia. Its reported prevalence is...
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Evaluation of Challenges in Diagnosis of Spontaneous Subacute Pyogenic Spondylodiscitis in Immunocompetent Patients: Experiences from a Tertiary Care Center

Pandita N, Paul S, Yadav G, Kalia RB, Kandwal P

STUDY DESIGN: Prospective clinical study. PURPOSE: We evaluated the challenges faced during diagnosis and management of patients with subacute pyogenic discitis and discussed various clues in clinical history, radiologic and hematologic...
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Clinical Results of Subtotal Fasciectomy for Treatment of Dupuytren Contracture

Lee YM, Song SW, Kim YW, Choi JH

PURPOSE: In the treatment of Dupuytren's contracture, the aim of optical treatment is to lower the recurrence rate and reduce complications. This paper reports the results of subtotal fasciectomy in...
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