Korean J Obstet Gynecol.  1997 Nov;40(11):2430-2436.

Comparison of the Expression of Transforming Growth Factor-beta in Microsurgical Reananstomosis of Rabbit Fallopian Tube

• Kim CH
• Rho SH
• Kim EJ
• Chung KW
• Kwon DJ
• Kim JH
• Lee JW
• Kim SP

Abstract

Twenty seven rabbits were divided into 3 groups of 1, 2-1 and 2-2(n=9 in each group). Arbitarilly cut ends of mid-ampullar portion of each tubes were microscopically reanastomosed using vicryl as suture material without intraluminal splint in group 1, using vicryl as suture material with intraluminal splint in group 2-1 and coagulation by Nd-YAG Laser beam as refusion method with intraluminal splint in group 2-2. A week after operation, the tubal tissue segments of reanastomosis were embedded into paraffin to examine the expression rate and intensity of TGF-beta1, 2 and 3 by immunohistochemical staining. The results were as follows. 1. The expression rate of TGF-beta1, 2 and 3 revealed no stastically significant difference between group 1 and 2. 2. Among comparisons group 2-1 and 2-2, the TGF-beta1 expression rate in group 2-2 showed lower value than that in group 2-1 with stastical significance(P<0.05). The above fact that tuboplasty with Nd-YAG Laser using intraluminal splint resulted in lower expression rate of TGF beta1 may suggest raising the succe ss rate of pregnancy.

MeSH Terms

Fallopian Tubes*
Female
Lasers, Solid-State
Paraffin
Polyglactin 910
Pregnancy
Rabbits
Splints
Sutures
Transforming Growth Factor beta1
Paraffin
Polyglactin 910
Transforming Growth Factor beta1