Clinical Observation on Carcinoma of the Prostate

Koo, Dug Cheon; Min, Byung Kap

Abstract

Nineteen patients of carcinoma of the prostate admitted to the Department of Urology, Chonnam University Medical School, between 1977 and 1981 were reviewed linically. The following results were obtained. 1. The average age of the patients was 68.6 years, with a range of 25 to 85 years. 2. The average duration from onset of the symptoms to admission was 8 months, with a range of 8 days to 4 years. The presenting symptoms were of prostatic obstruction in 17 cages (89.5%), gross hematuria in 3 cases (15.8%) and bone pain in 3 cases (15.8%). 3. Serum acid phosphatase level was elevated in 7 of 19 patients, 5 of whom had distant metastasis. Serum alkaline phosphatase level was elevated in 5 of 19 patients, 2 of whom had osteoblastic bony metastasis. 4. Biopsy of the prostate was performed by transrectal needle biopsy in 8 cases, transperineal needle biopsy in 2 cases and transurethral resection in 3 cages. All cases were revealed adenocarcinoma of the prostate. In 6 cases adenocarcinoma of the prostate was found within the hyperplastic benign prostatic lobes. 5. Orchiectomy was done in 5 cases and endocrine therapy was done in 13 cases. 6. Follow-up studies were performed clinically in 11 cages ranging in duration from 4 months to 42 months. During this period 3 patients died in 10 months, 11 months and 24 months after operation, respectively.