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Long-term Surgical and Chemical Castration Deteriorates Memory Function Through Downregulation of PKA/CREB/BDNF and c-Raf/MEK/ERK Pathways in Hippocampus

Shin MS, Kim TW, Park SS, Ko IG, Kim CJ, Kim M, Roh SY, Kim KT, Kim KH

PURPOSE: Goserelin is a drug used for chemical castration. In a rat model, we investigated whether surgical and chemical castration affected memory ability through the protein kinase A (PKA)/cyclic adenosine...
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Calcaneal Osteomyelitis Presenting as a Paradoxical Reaction during Treatment of Multidrug-Resistant Tuberculosis

Han YH, Lee CH, Bae MJ, Hwang K

Tuberculosis in the foot progresses gradually; thus, diagnosis is usually delayed, and early treatment is rarely provided. If osteomyelitis occurs due to delayed diagnosis and treatment, surgical treatment should be...
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Anemic Retinopathy after Chemotherapy

Lee SC, Oh BL

PURPOSE: To report a case of anemic retinopathy after chemotherapy. CASE SUMMARY: A 32-year-old male presented with visual disturbance in both eyes. He had been diagnosed with testicular cancer and had...
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Neutrophil-Lymphocyte Ratio Predicts Organ Salvage in Testicular Torsion with Marginal Diagnostic Delay

Jang JB, Ko YH, Choi JY, Song PH, Moon KH, Jung HC

PURPOSE: Though prompt diagnosis to minimize symptom duration (SD) is highly associated with organ salvage in cases of testicular torsion (TT), SD is subjective and hard to determine. We thus...
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Myxoid Liposarcoma of Spermatic Cord Misdiagnosed for Hemangioma

Kim YJ

Myxoid liposarcoma arose from the spermatic cord is very rare. Also, it is difficult to diagnose by clinical findings or radiologic study. Even if it was a malignant tumor, scrotal...
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Add-on Therapy With the α-Blockers Tamsulosin and Naftopidil Improves Voiding Function by Enhancing Neuronal Activity in Prostatic Hyperplasia Rats

Ko IG, Hwang L, Jin JJ, Kim SH, Han JH, Jeon JW, Cho ST

PURPOSE: Benign prostatic hyperplasia (BPH) impacts quality of life in men by causing lower urinary tract symptoms. α1-Adrenoceptor (α1-AR) blockers improve lower urinary tract symptoms. We investigated the efficacy of...
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Successful onco-testicular sperm extraction from a testicular cancer patient with a single testis and azoospermia

Kuroda S, Kondo T, Mori K, Yasuda K, Asai T, Sanjo H, Yakanaka H, Takeshima , Kawahara T, Kato Y, Miyoshi Y, Uemura H, Iwasaki A, Yumura Y

Onco-testicular sperm extraction is used to preserve fertility in patients with bilateral testicular tumors and azoospermia. We report the case of a testicular tumor in the solitary testis of a...
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Histomorphological changes in the common carotid artery of the male rat in induced hypogonadism

Cheruiyot , Olabu B, Kamau M, Ongeti K, Mandela P

The role of androgens in the development of cardiovascular diseases remains controversial. The current study therefore sought to determine the changes in the histomorphology of the common carotid artery of...
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Use of remifentanil and propofol without muscle relaxant with Duchenne muscular dystrophy: A case report

Kim HS, Baek SY, Park DH, Ryu KH

Duchenne muscular dystrophy (DMD) is a relatively rare muscle disease with severe symptoms. Owing to the commonly limited mouth opening, cervical spine immobility, and deformation, DMD patients often present with...
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Clinical Outcomes of Continuous Addition of Androgen Deprivation Therapy During Docetaxel Chemotherapy for Patients With Castration-Resistant Prostate Cancer

Lee DH, Kim JH, Seo WI, Nam JK, Kim TN, Oh CK, Kim SD, Park SW, Chung JS, Park SH, Lee W, Sung GT, Chung MK, Chung JI

PURPOSE: This study compared the oncologic results of docetaxel chemotherapy (DOC) in castration-resistant prostate cancer (CRPC) according to continuous addition of androgen deprivation therapy (ADT) during chemotherapy. MATERIALS AND METHODS: We...
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Usefulness of Tc-99m Pertechnetate SPECT/CT in the Diagnosis of Testicular Infarction After Inguinal Herniorrhaphy

Kim MH, Kim CG, Park SA, Kim DW

A 77-year-old male underwent open repair for a right indirect inguinal hernia and complained of right scrotal pain on the third postoperative day. Color Doppler imaging revealed decreased blood flow...
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Corn silk extract improves benign prostatic hyperplasia in experimental rat model

Kim SR, Ha AW, Choi HJ, Kim SL, Kang HJ, Kim MH, Kim WK

BACKGROUND/OBJECTIVES: This study was conducted to investigate the effect of a corn silk extract on improving benign prostatic hyperplasia (BPH). MATERIALS/METHODS: The experimental animals, 6-week-old male Wistar rats, were divided into...
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Differential expression of estrogen receptor α and progesterone receptor in the normal and cryptorchid testis of a dog

Jung HY, Yoo DY, Jo YK, Kim GA, Chung JY, Choi JH, Jang G, Hwang IK

Descending of the testes is an important process for spermatogenesis and cryptorchidism is one of the most relevant genital defects in dogs. In a previous study, we observed abnormal morphology...
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The histologic features of intratubular germ cell neoplasia and its correlation with tumor behavior

Basiri A, Movahhed S, Parvin M, Salimi M, Rezaeetalab GH

PURPOSE: To assess the prevalence of intratubular germ cell neoplasia (ITGCN) in patients with concurrent testis tumor and its correlation with histologic features and serum tumor markers. MATERIALS AND METHODS: From...
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Predictive Parameters of Testicular Salvage of Pediatric Testicular Torsion: A 6-Year Experience of a Single Center

Lee S, Park BK, Chung MK, Chung JM, Lee SD

PURPOSE: We evaluated parameters associated with testicular salvage in boys with testicular torsion. MATERIALS AND METHODS: During 2009-2014, 19 boys younger than 18 years old underwent emergency surgery for testicular torsion...
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Changes in Bone Metabolism in Young Castrated Male Rats

Ryu SJ, Ryu DS, Kim JY, Park JY, Kim KH, Chin DK, Kim KS, Cho YE, Kuh SU

PURPOSE: To determine the window of time during which osteoporosis affects the management of spinal surgery and the mechanism of bone metabolism changes in males with osteoporosis by examining changes...
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Commentary on "A Case of Paratesticular Leiomyosarcoma Successfully Treated with Orchiectomy and Chemotherapy"

Virgilio E, Uccini S, Marchetti , Mercantini P

No abstract available.
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The Testis Completely Replaced by a Huge Epidermal Cyst in an Older Man

Park KK, Hyun CL, Kim SD, Kim YJ, Huh JS

Epidermal cysts are commonly encountered, slow-growing superficial cysts in the hair-bearing areas of the body, and are usually discovered in the second and fourth decades of life. These cysts tend...
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Robot-assisted laparoscopic retroperitoneal lymph node dissection for stage IIIb mixed germ cell testicular cancer after chemotherapy

Lee SH, Kim DS, Chang SG, Jeon SH

Laparoscopic retroperitoneal lymph node dissection, especially when performed with the da Vinci Surgical System (Intuitive Surgical), has shown excellent cosmetic results with similar oncologic outcomes to those of open surgery....
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The incidence and histological characteristics of intratubular germ cell neoplasia in postpubertal cryptorchid testis

Ryang SH, Jung JH, Eom M, Song JM, Chung HC, Chae Y, Lee CM, Kim KJ

PURPOSE: It is well known that testicular germ cell tumors arise with increased frequency in patients with cryptorchidism. In addition, intratubular germ cell neoplasia (ITGCN) is a precursor lesion to...
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