Cancer Res Treat.  2016 Jan;48(1):422-424. 10.4143/crt.2015.175.

Commentary on "A Case of Paratesticular Leiomyosarcoma Successfully Treated with Orchiectomy and Chemotherapy"

Affiliations
  • 1Department of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology "Sapienza", St. Andrea Hospital, Rome, Italy. aresedo1992@yahoo.it
  • 2Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology "Sapienza", St. Andrea Hospital, Rome, Italy.

Abstract

No abstract available.


MeSH Terms

Leiomyosarcoma*
Orchiectomy*

Figure

  • Fig. 1. (A) 18-Fluoro-2-deoxyglucose positron emission tomography–computed tomography scan showed two right external iliac centimetric lymph nodes with an increased maximum standardized uptake value (of 14 and 4, red color with yellow halo). (B) Immunohistochemistry of the metastases revealed leiomyosarcoma consistent with the histological findings of the previous lesion of the spermatic cord (Ki-67 index of 10% and staining positive for smooth muscle actin but negative for S100 protein) (cross section, H&E staining, ×63).

  • Fig. 2. (A) 18-Fluoro-2-deoxyglucose positron emission tomography–computed tomography scan detected two centimetric nodules in the perineal and sovrapubic area (maximum standardized uptake value less than 2.0, white color with green halo). (B) Histological examination yielded the diagnosis of metastatic soft tissue tumor, but, of interest, excluded the well differentiated leiomyosarcomatous in favour of a dedifferentiated liposarcomatous phenotype (G2, Ki-67 30%, smooth muscle actin–negative but S-100- and MDM2-positive) (cross section, H&E staining, ×63).


Reference

References

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