Korean J Urol.  1986 Feb;27(1):45-48.

Effect of Subcapsular Orchiectomy on Serum Testosterone in Rats

• Suh JK
• Park TC

Abstract

The subcapsular orchiectomy is far more acceptable than a total orchiectomy to patients with prostatic carcinoma. To data, however, it has not been widely used clinically, because its effectiveness in reducing serum androgen levels has remained controversial. We designed this study, to determine if a subcapsular orchiectomy might be as effective as the total orchiectomy in lowering serum testosterone levels, with a controlled rat model. The results support that the subcapsular orchiectomy is as hormonally complete as a total orchiectomy in lowering serum testosterone, and provide us with a basic guideline to be applied to clinical management for prostatic carcinoma.

Keyword

subcapsular orchiectomy; testosterone

MeSH Terms

Animals
Humans
Models, Animal
Orchiectomy*
Rats*
Testosterone*
Testosterone