Korean J Urol.
1991 Apr;32(2):349-352.
Primary small cell carcinoma of the prostate
- Affiliations
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- 1Department of Urology, Gang Nam General Hospital, Korea.
- 2Department of Pathology, Seoul National University, Hospital, Seoul, Korea.
Abstract
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Primary small cell carcinomas of the prostate are rare, and their histogenesis and clinical behavior remain poorly defined. The origin of small cell carcinoma remains uncertain, but several hypothesis has been put forward, one of this is that the tumor is derived from the argentaffin or argyrophil cells normally present in the prostate, and the other is that arises from the totipotential basal or reserve cells of the prostatic acini. Primary small cell carcinoma of the prostate is a highly aggressive tumor. causing widespread metastasis and early death. The mean survival is 5 to7 months after diagnosis of the small cell carcinoma regardless of the proportion of small cell component or cell size. We report one case of primary small cell carcinoma of the prostate with brief review of literatures.