Res Vestib Sci.
2014 Jun;13(2):53-56.
A Case of Creutzfeldt-Jakob Disease Presenting Mainly with Abnormal Eye Movements
- Affiliations
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- 1Department of Neurology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea. xorudoc@schmc.ac.kr
Abstract
- Creutzfeldt-Jakob disease (CJD) is a human prion disease with rapidly progressive neurodegeneration. The major clinical manifestations of CJD include mental deterioration, myoclonus, cerebellar dysfunction, and neuro-ophthalmic symptoms and signs. However, abnormal eye movements as an early sign of CJD are rare. We report a 49-year-old man with periodic alternating nystagmus in early disease course.