J Korean Radiol Soc.  1994 Aug;31(2):331-335.

Transfusional Hemosiderosis; Correlation of MR Findings with Clinical Findings

Abstract

PURPOSE
Parenchymal iron deposition occurs in hemochromatosis, while iron is deposited in reticuloendothelial cells after blood transfusions(Hemosiderosis). We stuided correlation between MR finding and clinical findings(serum ferritin, TSI, LFT, disease duration) of hemosiderosis.
MATERIALS AND METHODS
12 patients with chronic renal failure and one patient with aplastic anemia, who have received multiple transfusion, were performed MRI with a 2.0 Tesla unit.
RESULTS
In All of 13 patients(17 cases), the liver revealed low signal intensity equal to background noise. In 4 of 17 cases whose serum ferritin level was below 1000 ng/ml, pancreas, gastric wall, adrenal gland were involved in 1 case. In 4 cases with serum ferritin level between 1000 and 1500, pancreas was involved in 2 cases, and other organ was involved in 1 case. In 9 cases with serum ferritin level above 1500ng/ml, pancreas involved in 9 cases, and other organ in 4 cases.
CONCLUSIONS
The MR findings are well correlated with serum ferritin level whereas the TSI, LFT, disease duration are not correlated with involved organ on MR.


MeSH Terms

Adrenal Glands
Anemia, Aplastic
Ferritins
Hemochromatosis
Hemosiderosis*
Humans
Iron
Kidney Failure, Chronic
Liver
Magnetic Resonance Imaging
Noise
Pancreas
Ferritins
Iron
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