Korean J Obstet Gynecol.  2001 Jul;44(7):1291-1295.

A clinical study on fetuses and neonates with single umbilical artery

Affiliations
  • 1Department of obstetrics & gynecology, Ilsin christian hospital, Pusan, Korea.

Abstract


OBJECTIVE
To evaluate the relationship of single umbilical artery with congenital anomaly, chromosomal anomaly & pregnancy outcome.
METHODS
From January 1993 to December 2000, 143 cases of single umbilical artery were observed among 72,194 total deliveries at Ilsin christian hospital. Pregnancy and perinatal outcome data were retrieved by review of the medical records.
RESULTS
The incidence of single umbilical artery (SUA) was 0.2% (143 cases). Isolated SUA without any anomaly were 89 cases (62.2%), SUA with anomaly were 42 cases (29.4%) ; with multiple anomaly were 20 (14%) and stillbirth were 12 (8.4%). Cardiovascular & musculoskeletal system anomalies were common congenital anomalies, 35.7% respectively. Among the 86 cases (60.1%) of chromosomal studies, chromosomal anomalies were observed in 4 cases (2.8%) ; 2 cases were Trisomy 18, 2 cases were 45,XX,-13,-14,+t (13q:14q), 46,XY,t(1:9) (q11:q11). No chromosomal anomaly was observed in isolated SUA without any other anomaly. On 74cases with obstetric complication, intrauterine growth restriction (n=27, 20.6%), preterm birth (n=12, 10%), hydramnios (n=11, 8.4%), oligohydramnios (n=7, 5.3%), preeclampsia (n=6, 4.6%), maternal gestational DM (n=5, 3.8%) were observed.
CONCLUSION
When a single umbilical artery is identified during antenatal care, careful search such as targeted ultrasonography & fetal echocardiography should be taken for associated anomaly, and chromosomal study should be considered in case of SUA with any anomaly.

Keyword

single umbilical artery; congenital anomalies; chromosomal anomalies

MeSH Terms

Echocardiography
Female
Fetus*
Humans
Incidence
Infant, Newborn*
Medical Records
Musculoskeletal System
Oligohydramnios
Polyhydramnios
Pre-Eclampsia
Pregnancy
Pregnancy Outcome
Premature Birth
Single Umbilical Artery*
Stillbirth
Trisomy
Ultrasonography
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