Korean J Perinatol.  1999 Jun;10(2):155-160.

Perinatal Prognosis of Single Umbilical Artery

• Kim YH
• Song TB
• Byun JS
• Choi YY
• Lee JY

Abstract

OBJECTIVE
To evaluate the perinatal prognosis of fetuses with a single umbilical artery.
METHODS
From 1992 to 1998, nineteen cases with single umbilical artery(SUA) was observed in 8,704 deliveries at Chonnam University Hospital.
RESULTS
Out of nineteen fetuses, thirteen fetuses with single umbilical artery were detected by antenatal ultrasonographic examination and six fetuses were detected after birth. The male to female ratio was 0.9: 1. Congenital malformations were observed in 8 babies(42.1%) and included leg deformity, esophageal atresia, imperforated anus, ventriculomegaly, meningocele, hydronephrosis, ventricular septal defect, joint contracture, cleft lip and palate, toe anomaly, imperforated anus, kyphosis, no urethra and testis, clubfoot, patent ductus arteriosus and rnild mitral regurgitation. Among 10 cases of karyotyping analysis three cases were diagnosed as trisomy 18. Fourteen fetuses(77.8%) showed growth restriction at delivery. Antenatal obstetric complications were hydramnios(n = 3), oligohydramnios(n =2), and severe preeclampsia(n = 3).
CONCLUSION
Careful ultrasonographic evaluation for the identification of a SUA is necessary because of its frequent association with congenital anomaly, growth restriction and cytogenetic abnormality.

Keyword

Single umbilical artery; Congenital anomaly; Intrauterine growth restriction

MeSH Terms

Anal Canal
Chromosome Aberrations
Cleft Lip
Clubfoot
Congenital Abnormalities
Contracture
Ductus Arteriosus, Patent
Esophageal Atresia
Female
Fetus
Heart Septal Defects, Ventricular
Humans
Hydronephrosis
Jeollanam-do
Joints
Karyotyping
Kyphosis
Leg
Male
Meningocele
Mitral Valve Insufficiency
Palate
Parturition
Prognosis*
Single Umbilical Artery*
Testis
Toes
Trisomy
Urethra