Anesth Pain Med.  2007 Oct;2(4):242-245.

General Anesthesia for Cesarean Section of a Parturient with Aplastic Anemia Refractory to Platelet Transfusion

• Lee HS
• Lee HJ

Abstract

Aplastic anemia is pancytopenia with bone marrow hypocellularity. The major risks to the pregnant women with aplastic anemia are hemorrhage and infection. Mortality during or after pregnancy is very high, especially thrombocytopenia complicated by platelet refractoriness, due to bleeding and sepsis. There is no therapeutic guideline for aplastic anemia with platelet refractoriness about cesarean section. A multidisciplinary approach to patients with aplastic anemia refractory to platelet transfusion is essential. Close consultation among the hematologist, anesthesiologist and obstetrician, and a management plan are important. We report the successful management of such a patient during cesarean section under general anesthesia.

Keyword

aplastic anemia; cesarean section; general anesthesia; platelet refractoriness; thrombocytopenia

MeSH Terms

Anemia, Aplastic*
Anesthesia, General*
Blood Platelets*
Bone Marrow
Cesarean Section*
Female
Hemorrhage
Humans
Mortality
Pancytopenia
Platelet Transfusion*
Pregnancy
Pregnant Women
Sepsis
Thrombocytopenia