Tuberc Respir Dis.  2002 Dec;53(6):656-661. 10.4046/trd.2002.53.6.656.

A Case of Amiodarone-Induced Pulmonary Toxicity After a Long Course of a Low Dose Therapy

Affiliations
  • 1Department of Internal Medicine, College of Medicine, Catholic University of Daegu, Daegu, Korea. trshin@cuth.cataegu.ac.kr

Abstract

Amidarone is one of the most commonly prescribed anti-arrythmic agents for almost all arrythmias, whether atrial or ventricular in origin. There are several side effects associated with amiodarone therapy. These include corneal deposits, abnormal liver function tests, hyper and hypothyroidism, bluish discolorations of the skin, bone marrow suppression, coagulopathies, peripheral neuropathies, and pulmonary toxicity. Amiodarone-induced pulmonary toxicity(APT), which was first described in 1980, is potentially serious side effects that are believed to develop in 5% of patients. Doctors often assume that APT occurs only when high amiodarone doses are used for a long time, but in practice a low maintenance dose of amiodarone may also be toxic. In this report, a case of amiodarone-induced pulmonary toxicity after a long course of a low dose therapy for refractory supraventricular arrythmia is described.

Keyword

Amiodarone; Pulmonary toxicity

MeSH Terms

Amiodarone
Arrhythmias, Cardiac
Bone Marrow
Humans
Hypothyroidism
Liver Function Tests
Peripheral Nervous System Diseases
Skin
Amiodarone
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