J Korean Acad Fam Med.
2007 Jun;28(6):460-465.
A Case Report of Amiodarone-induced Multiple Toxicity after a Long Course of a Low Dose Therapy
- Affiliations
-
- 1Department of Family Medicine, Hanyang University College of Medicine, Seoul, Korea. fmhwang@hanyang.ac.kr
- 2Department of Diagnostic Radiology, Hanyang University College of Medicine, Seoul, Korea.
Abstract
- Amiodarone is a potent antiarrhythmic agent that is used to treat ventricular arrhythmias and atrial fibrillation. But it has a wide range of adverse effects, including pulmonary toxicity, thyroid dysfunction, liver toxicity, gastrointestinal events, corneal deposits, peripheral neuropathy and so on. Patients treated with amiodarone should be followed regularly to assess ongoing need for amiodarone, efficacy of the drug, appropriateness of dosage, adverse effects, and potential drug interactions. We experienced a case of severe weight loss due to amiodarone-induced multiple toxicity after a long course of a low dose therapy. So we report this unusual case with literature review.