Diabetes Metab J.  2011 Oct;35(5):543-550. 10.4093/dmj.2011.35.5.543.

The Prevalence of Peripheral Arterial Disease in Korean Patients with Type 2 Diabetes Mellitus Attending a University Hospital

• Yu JH
• Hwang JY
• Shin MS
• Jung CH
• Kim EH
• Lee SA
• Koh EH
• Lee WJ
• Kim MS
• Park JY
• Lee KU

• KMID: 1857511
• DOI: http://doi.org/10.4093/dmj.2011.35.5.543

Abstract

BACKGROUND
Peripheral arterial disease (PAD) is a common manifestation of systemic atherosclerosis and is associated with significant morbidity and mortality. Diabetes is known to increase the risk of PAD two- to four-fold. The prevalence of PAD in Korean diabetic patients has not been established. In this study, we investigated the prevalence of PAD in Korean patients with type 2 diabetes attending a large university hospital and analyzed the factors associated with PAD.
METHODS
A total of 2,002 patients with type 2 diabetes who underwent ankle-brachial index (ABI) measurement in an outpatient clinic were enrolled. PAD was defined as an ABI < or =0.9. Clinical characteristics of 64 patients with PAD were compared with those of 192 age- and sex-matched control patients without PAD.
RESULTS
Of the 2,002 type 2 diabetic patients, 64 (3.2%) were diagnosed as having PAD. PAD was associated with higher prevalences of retinopathy, nephropathy, neuropathy, cerebrovascular and coronary artery disease. Patients with PAD had higher systolic blood pressure and serum triglyceride level and reported higher pack-years of smoking. Multivariate analysis showed that the presence of micro- and macrovascular complications and high systolic blood pressure are factors independently associated with PAD.
CONCLUSION
The prevalence of PAD in diabetic patients was 3.2%, suggesting that the prevalence in Korean diabetic patients is lower than that of patients in Western countries.

Keyword

Diabetes mellitus, type 2; Peripheral arterial disease; Prevalence; Risk factors

MeSH Terms

Ambulatory Care Facilities
Ankle Brachial Index
Atherosclerosis
Blood Pressure
Coronary Artery Disease
Diabetes Mellitus, Type 2
Humans
Multivariate Analysis
Peripheral Arterial Disease
Prevalence
Risk Factors
Smoke
Smoking
Smoke

Figure

• 

  Fig. 1 The prevalence rates of peripheral arterial disease according to age and sex.

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