Korean J Pediatr.  2010 Jan;53(1):48-55. 10.3345/kjp.2010.53.1.48.

Regional outbreak of staphylococcal scalded skin syndrome in healthy children

Affiliations
  • 1Department of Pediatrics, Gyeongsang National University College of Medicine, Jinju, Korea. seozee@gnu.ac.kr

Abstract

PURPOSE
Staphylococcal scalded skin syndrome (SSSS) is a relatively uncommon superficial blistering skin disease that is due to Staphylococcus aureus. We had experienced a regional outbreak of SSSS over 3 years in healthy children.
METHODS
We retrospectively reviewed the medical records of those patients diagnosed as SSSS. Most of neonatal cases were nosocomial infections and excluded from the analysis. The clinical features, laboratory findings, the isolation and antibiotic resistance of S. aureus, the antibiotic management and other supportive treatments were analyzed.
RESULTS
Fifty-five patients with SSSS were admitted to our hospital from October 2001 to September 2004. The median age of patients was 3.0 years. Of the 55 patients, 9 were the generalized type, 13 were the intermediate type and 33 were the scarletiniform rash. All the patients were living in neighborhood of the Jinju area. S. aureus were isolated from 9 of the patients and all of the isolated S. aureus were methicillin resistant. All the patients except two were treated with intravenous flocloxacillin or nafcillin and/or cefotaxime. All the patients recovered during the follow-up period of 2 to 3 weeks.
CONCLUSION
We experienced a regional outbreak of SSSS in previous healthy children. Further study for finding the carriers of S. aureus caused SSSS and preventing the spread of this disease is needed. Additionally, guidelines for treating SSSS due to methicillin resistant S. aureus should be established.

Keyword

Staphylococcal Scaled Skin Syndrome; Outbreak; Methicillin Resistant Staphylococcus aureus

MeSH Terms

Blister
Cefotaxime
Child
Cross Infection
Drug Resistance, Microbial
Exanthema
Follow-Up Studies
Humans
Medical Records
Methicillin Resistance
Nafcillin
Residence Characteristics
Retrospective Studies
Skin Diseases
Staphylococcal Scalded Skin Syndrome
Staphylococcus aureus
Cefotaxime
Nafcillin
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