Korean J Obstet Gynecol.  2010 Nov;53(11):1024-1027. 10.5468/kjog.2010.53.11.1024.

Video-assisted thoracoscopic surgery for pulmonary metastasis of gestational trophoblastic neoplasia

• Kim YS
• Kwak HM
• Kim SH
• Choi CH
• Lee JW
• Bae DS

• KMID: 1836718
• DOI: http://doi.org/10.5468/kjog.2010.53.11.1024

Abstract

Gestational trophoblastic neoplasm (GTN) is prone to pulmonary metastasis. Although most pulmonary metastatic lesions response with chemotherapy, some lesions do not resolve and persist on radiologic investigations. A 25-year-old women was referred for persistent pulmonary metastatic lesion of GTN. Here, we present a case of chemo-resistant choriocarcinoma metastatic to lung managed by video-assisted thoracoscopic surgery.

Keyword

Gestational trophoblastic neoplasm; Thoracic surgery; Video-assisted

MeSH Terms

Adult
Choriocarcinoma
Female
Gestational Trophoblastic Disease
Humans
Lung
Neoplasm Metastasis
Pregnancy
Thoracic Surgery
Thoracic Surgery, Video-Assisted

Figure

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  Figure 1 (A) Positron emission tomography showing pulmonary metastasis of left upper lobe. (B) Chest computerized tomography showing pulmonary metastasis.

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  Figure 2 (A) Low power view of microscopic finding shows diffuse hemorrhage and necrosis of the tumor (×40). (B) The tumor is composed of cytotrophoblast and syncytiotrophoblastic giant cells with irregular arrangement (×200). (C) Immunohistochemical stain for β-hCG highlights the cytoplasm of the syncytiotrophoblastic giant cells (hCG ×400).

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